Foodborne trematodiasis fbt is a significant global health problem, with the liver flukes opisthorchis viverrini, o. Opisthorchis felineus, or cat liver fluke is a trematode parasite that infects the liver in mammals. Opisthorchis felineus is a trematode that is transmitted to humans through the consumption of raw freshwater fish of the family cyprinidae. May first report and molecular identification of opisthorchis viverrini infection in human communities from lower myanmar win pa pa aung 0 1 2 thi thi htoon 0 2 htay htay tin 0 2 kyi kyi thinn 0 2 oranuch sanpool 0 1 2 jurairat jongthawin 0 1 2 lakkhana sadaow 0 1 2 issarapong phosuk 0 1 2 rutchanee rodpai 0 1 2 pewpan m.
Fish sharing as a risk factor for opisthorchis viverrini. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree. What are the signs and symptoms of opisthorchiasis. Human illnesses caused by opisthorchis felineus flukes, italy. Opisthorchis felineus an overview sciencedirect topics opisthorchis twitter search opisthorchis felineus in cat. Infection with the parasite is called opisthorchiasis. Histological analysis of the liver of uninfected hamster control. Links with this icon indicate that you are leaving the cdc website the centers for disease control and prevention cdc cannot attest to the accuracy of a nonfederal website.
After ingestion by a suitable snail first intermediate host, the eggs release miracidia, which undergo in the snail several developmental stages sporocysts, rediae. Hemozoin is the pigment produced by some bloodfeeding parasites. They are genetically related to other opisthorchid flukes of cats, including clonorchis sinensis opisthorchis spp have been recorded frequently in russia, the ukraine and kazakhstan. An integrated epidemiological study of opisthorchis viverrini consisting of risk factors analysis and parasitation prevalence determination in humans, as well as the assessment the roles of host reservoirs dogs and cats and intermediate hosts cyprinid fish was carried out in the vicinity of huay luang dam, udon thani province, in the north east of thailand. Ty jour t1 opisthorchis felineus, an emerging infection in italy and its implication for the european union. Hemozoin knobs in opisthorchis felineus infected liver. Opisthorchis felineus small biliary fluke, causing opisthorchiasis. Opisthorchis felineus, a hepatic trematode, is the causative agent of opisthorchiasis, a dangerous disease in both human beings and animals.
The purpose of the present study was to determine the complete mitochondrial dna sequence of this flatworm. Since then, cases of opisthorchiasis were reported each year. Felineus in western siberia, cca was detected in 77% of patients with opisthorchiasis. In 1891, russian parasitologist, konstantin nikolaevich vinogradov 18471906 found it in a human, and named the parasite a siberian liver fluke.
Macrophotograph of the liver of uninfected hamster control at a 5, b 24 and c 48 weeks after the start of the experiment. Trematodes flukes opisthorchis viverrini southeast asian liver fluke and opisthorchis felineus cat liver fluke. Foodborne trematodiasis and opisthorchis felineus acquired in. In the 1930s, helminthologist hans vogel of hamburg. Opisthorchiasis caused by foodborne trematode opisthorchis felineus is a substantial public health problem, with 17 million persons infected worldwide. The infection is associated with a number of hepatobiliary diseases, including cholangitis, obstructive jaundice, hepatomegaly, cholecystitis, cholelithiasis and. A high prevalence has been reported in byelorussia, russia, and the ukraine. Opisthorchis definition of opisthorchis by medical. They have a knob at the abopercular end that may be prominent, inconspicuous, or absent. In 1927, prommas identified the worms found at an autopsy of a 17yearold thai male residing in roiet, northeast thailand, as o. Infection of the definitive host follows the consumption of fish contaminated with metacercariae. Epidemiology of opisthorchis viverrini in an endemic area. When present, symptoms fever, nausea, abdominal pain, an. Clonorchis sinensis, opisthorchis spp, and metorchis spp.
Health, general fluke infections care and treatment case studies diagnosis. Opisthorchiasis is a hepatobiliary disease caused by flukes of the trematode family opisthorchiidae. Genetic variability of west siberian populations of opisthorchis felineus and two species of cyprinid fish, its second intermediate hosts, was studied by isozyme analysis. Population structure of opisthorchis felineus trematoda.
It was first discovered in 1884 in a cats liver by sebastiano rivolta of italy. Low levels of allozyme variation and genetic differentiation in o. On the basis of fish population estimation and studies on its invasion with opisthorchis felineus rivolta. If the inline pdf is not rendering correctly, you can download the pdf file here. Au pozio,edoardo, au armignacco,orlando, au ferri,fabrizio, au gomez morales,maria angeles, y1 20118 py 20120919received py 20107revised py 20109accepted py 20123entrez py 20123pubmed py 20821medline sp 54 ep 62 jf acta. Letters, clinical report, letter to the editor by emerging infectious diseases. When present, symptoms fever, nausea, abdominal pain, and myalgias were mild. Opisthorchiasis genetic and rare diseases information. Most individuals infected with opisthorchiasis do not present any symptoms.
For language access assistance, contact the ncats public information officer. Infection with opisthorchis felineus induces intraepithelial. Opisthorchis felineus, opisthorchis viverrini, and clonorchis sinensis are epidemiologically significant representatives of the opisthorchiidae family. The liver fluke infection in thailand was caused by o. Epidemiology, diagnosis and control of opisthorchis felineus. Foodborne trematodiasis and opisthorchis felineus acquired in italy. Sep 17, 2015 hemozoin is the pigment produced by some bloodfeeding parasites. All structured data from the file and property namespaces is available under the creative commons cc0 license. Nine of these men had fever, nausea, abdominal pain, and myalgias. Epidemiology, diagnosis and control of opisthorchis. Opisthorchis felineus 20200510 20200510 tagged medical chemical corporation. Opisthorchis felineus has been documented in at least 12 countries of the european union, belarus, ukraine, and in western siberia russia. Opisthorchis felineus wikipedia, a enciclopedia livre.
This chronic disease is associated with hepatobiliary inflammation, cholangiocyte dysplasia, cholangiofibrosis, intraepithelial neoplasia, and even cholangiocarcinoma among chronically infected individuals. Individuals infected for a long time chronic may get serious illness. Complete sequencing of the mitochondrial genome of. Opisthorchis spp have been recorded frequently in russia, the ukraine and kazakhstan. Assessment and management of seafood safety and quality. Worldwide, the number of cases of human infection has been estimated to be 1. People are infected after eating raw or undercooked fish. Pdf opisthorchis viverrini and opisthorchis felineus. It demonstrates high diagnostic and therapeutic potential. Opisthorchis felineus life cycle 20200511 20200511 tagged life cycle of opisthorchis viverrini. Opisthorchiasis is widespread in russia, especially western siberia. Population structure of opisthorchis felineus trematoda and its second intermediate hosts cyprinid fishes in the obirtysh focus of opisthorchiasis, based on allozyme data.
Infeetion with livr flukes opisthorchis viverrini, opisthorchis felineus and clonorchis sinensis 1. Opisthorchis felineus life cycle pixelmasterdesign. Pdf on jan 1, 2014, paiboon sithithaworn and others published opisthorchis viverrini and opisthorchis felineus find, read and cite all the research you need on researchgate. Opisthorchis sinensis definition of opisthorchis sinensis. Chromosomal disarrangement and immunoreactivity of golden hamsters infected with opisthorchis felineus by ginovker.
They are genetically related to other opisthorchid flukes of cats, including clonorchis sinensis. The term fluke means flatfish, since these parasites are flat. Opisthorchiasis caused by opisthorchis viverrini o. They need to be ingested by freshwater gastropod snail, the first intermediate host, to develop into sporocysts, rediae, and freeswimming cercariae, the stage infective for the second intermediate host, cyprinoid fish 3, 7.
This parasite is a biliary ductdwelling trematode that can. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126. Oct 20, 2014 opisthorchiasis is a trematode fluke infection caused by infection with one of the species of the liver fluke opisthorchis, which is acquired by eating raw or undercooked freshwater fish containing infectious metacercariae. These liver flukes are known to cause serious human diseases affecting bile ducts and the gall bladder. If you have problems viewing pdf files, download the latest version of adobe reader. Together they affect more than 45 million people and 600750 million people are at risk in the endemic regions of eurasia. Parasite liver and biliary tree parasites 69 cdc dpdx opisthorchiasis liver and biliary tree parasites 69 liver and biliary tree parasites 69.
Methorchis species are wide spread, and reported from north america, eurasia, and east asia. It is also present in puerto rico and possibly other caribbean islands. In this work the formation of cocalled hemozoin knobs the bile duct ectasia filled up by hemozoin pigment in opisthorhis felineus infected hamster liver has been observed. Opisthorchis felineus an overview sciencedirect topics. Liver fluke infection is recognized as the major risk. Opisthorchis felineus has a complex life cycle involving three hosts. First report and molecular identification of opisthorchis. Opisthorchis definition of opisthorchis by medical dictionary. Chromosomal disarrangement and immunoreactivity of golden. Opisthorchiasis is an infection caused by either of the two parasite worms, the cat liver fluke, or scientifically called opisthorchis felineus also known as opisthorchis tenuicollis, or the southeast asian liver fluke called as opisthorchis viverrini. All structured data from the file and property namespaces is available under the creative. Prime pubmed opisthorchis felineus, an emerging infection. This chronic disease is associated with hepatobiliary inflammation, cholangiocyte dysplasia, cholangiofibrosis, intraepithelial neoplasia, and even cholangiocarcinoma among chronically infected.
Linking to a nonfederal website does not constitute an endorsement by cdc or any of its employees of the sponsors or the information and products presented on the website. Characteristics of liver fibrosis associated with chronic. After ingestion by a suitable snail first intermediate host, the eggs release miracidia, which undergo in the snail several developmental stages. The adult flukes deposit fully developed eggs that are passed in the feces. The eggs are shed in the biliary tree of fisheating mammals and are passed with feces. Plasma metabolomics of the time resolved response to. Opisthorchis viverrini, common name southeast asian liver fluke, is a foodborne trematode parasite from the family opisthorchiidae that infects the bile duct. Opisthorchis felineus rivolta, 1884 is a member of the triad of epidemiologically important fishborne liver trematodes, which also includes o. We report 2 outbreaks of opisthorchis felineus infection caused by the consumption of tench filets tinca tinca from a lake in italy. Opisthorchis felineus is usually a parasite of cats, dogs, pigs, and whales, while opisthorchis viverrini is commonly found in dogs and cats. Opisthorchis viverrini, common name southeast asian liver fluke. Opisthorchis felineus infection provokes timedependent. Of the other 32 men who had attended the dinner at the private home, fecal samples of 18 were positive for opisthorchis sp. Opisthorchis felineus it is a trematode, a liver fluke it was described by rivolta in 1884 it has been detected in asia and europe to complete its natural cycle, egg one month in mammals o.
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